LeBron and Jaylen Brown play their first Sixers home game against Cleveland

LeBron James and Jaylen Brown play their first home game for the Philadelphia 76ers on Thursday night when the Cleveland Cavaliers visit Xfinity Mobile Arena. Tipoff is 7 p.m. ET on ESPN, the second night of the NBA season and the start of an ESPN doubleheader that ends with the Denver Nuggets at the Oklahoma City Thunder at 9:30 p.m. ET.

Philadelphia is 1-0 after beating the Knicks 106-100 at Madison Square Garden on Tuesday. Tyrese Maxey led the Sixers with 28 points, three steals and three blocks. Brown had 19 points, eight rebounds and six assists, and James had 14 points, nine rebounds and seven assists in his first game for Philadelphia. Joel Embiid added 13 points and 11 rebounds.

This is Cleveland's opener. Donovan Mitchell starts his 10th NBA season, and Peyton Watson makes his Cavaliers debut, per the NBA. ESPN lists Cavaliers center Jarrett Allen as day-to-day with a knee injury, with Khalifa Diop and Nae'Qwan Tomlin out. For the Sixers, Tacko Fall, Dominick Barlow and Ariel Hukporti are out and Dean Wade is day-to-day.

Philadelphia is a 2.5-point favorite with a total of 236.5, according to ESPN's odds feed.

Nuggets at Thunder, 9:30 p.m. ET, ESPN

The late game is Denver's first of the season and Oklahoma City's second. The Thunder won 116-104 at San Antonio on Tuesday behind 32 points, six rebounds, three steals and three blocks from Shai Gilgeous-Alexander.

Nikola Jokic leads Denver into Paycom Center. The Nuggets are without Julian Strawther, who has a knee injury, and list Spencer Jones as day-to-day with a hamstring injury. Oklahoma City is without Nikola Topic, Thomas Sorber and rookie Otega Oweh. The Thunder are 8.5-point favorites.

What to watch: how Philadelphia splits shots among Maxey, Brown, James and Embiid in front of its own crowd, whether Allen plays for Cleveland, and whether Jokic and Gilgeous-Alexander pick up where their March meeting left off, which the NBA called a duel that went to the final seconds.